International Journal of Cancer Management

  • ISSN: 2538-497X
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  • Journal Type: per-article | Frequency: monthly
  • Language: EN
  • Organization: International Journal of Cancer Management
Review Article
Marijana Tadic, Cesare Cuspidi
The incidence of breast malignancy is increasing and it became evident that chemotherapy protocols that are based on anthracyclines and trastuzumab, which are being used in these patients, have cardiotoxic effect. Traditional imaging methods could detect the advance stage of chemotherapy-induced cardiomyopathy when cardiac function is significantly ... read more
Research Article
Mehrdad Payandeh, Nasrin Amirifard, Edris Sadeghi, Masoud Sadeghi
Testicular germ cell tumors (TGCTs) account for only 1% - 2% of all male neoplasma.The aim of this study is to evaluate clinicopathological features, treatment options and overall survival (OS) in patients with TGCT in Kermanshah province, Iran.In this retrospective study, 39 patients that referred to oncology ... read more
Research Article
Zohreh Yousefi, Mansoureh Mottaghi, Sima Kadkhodayan, Malihe Hasanzadeh, Masoumeh Mottaghi, Monavar Afzalaghaee
Lymphatic spread is a common feature of ovarian cancer both in early and advanced stages of the disease. There is also a controversial problem of the impact of para-aortic lymph node dissection between gynecologist oncologist experts. The aim of this study is evaluating the effect of Para ... read more
Research Article
Nasim Dana, Mohammad Hasan Tajaddini, Shaghayegh Haghjooy Javanmard, Elham Jafari, Alireza Abed, Maryam Jamadi, Golnaz Vaseghi
Previous studies suggested that Cannabis sativa has anti-cancer properties influencing tumor size and metastasis properties. Microtubule associated proteins (MAPs) such as tau binds to the microtubules and leads to cancer metastasis. Stathmin is a cytosolic phosphor-protein which can induce the depolymerization of microtubules in cancer cell lines, ... read more
Research Article
Nesa Sayadnejad, Alireza Firouzjahi, Shahryar Shafaee, Hannaneh Golshahi, Zahra Sokouti, Hemmat Gholinia, Mohammad Ranaee
Human epidermal growth factor receptor 2 (HER2) overexpression and amplification have been studied as a therapeutic and prognostic target in a number of tumors although conflicting data exist about the incidence and clinical consequence of HER2/neu status in the patients with colorectal cancer. The aim of the ... read more
Research Article
Mayram Amiri-Shoar, Masoumeh Hosseini, Mitra Arianmanesh, Reza Eghdam-Zamiri, Shahrokh Attarian, Ali Awsat Mellati
There is very limited evidence about the differences between proteome of breast cancer tissue and the adjacent normal tissue. Given the importance of identifying factors involved in the tumorogenesis of breast cancer; herein we aimed to compare the proteome of HER2 negative invasive ductal carcinoma and their ... read more
Research Article
Zohreh Jaafari-Ashkavandi, Azadeh Hamedi, Sepideh Assar, Azin Ebrahimpour
Cytotoxic effects of Frankincense resin have been shown on some cancer cell lines. Due to its low side effects, this study was designed to evaluate the anticancer properties of water soluble elements of Frankincense oleo-gum-resin on human oral squamous cell carcinoma cell line.Oleo-gum-resin was macerated in ethanol. ... read more
Research Article
Bahareh Zarrin, Shaghayegh Haghjooy Javanmard, Fariba Samani, Mohamadhasan Tajadini, Maryam Jamady, Neda Esmaeli, Ahmed Ghasemi, Golnaz Vaseghi
Metastasis is one the most important causes of death among the patients diagnosed with breast cancer. Tau protein is a cytoskeletal protein which competes with paclitaxel and attenuates its effects. So increased tau protein may promote metastasis progression. Duloxetine is an antidepressant inhibiting serotonin, norepinephrine reuptake. In ... read more
Research Article
Azar Fani Pakdel, Bahram Memar, Kazem Anvari, Fatemeh Homaee Shandiz, Mahboobeh Sadeghi Ivari
Immunohistochemistry (IHC) of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (Her2) are important prognostic factors of breast cancer. However, discordance between IHC findings of primary tumor and ipsilateral metastatic lymph nodes (IMLNs) has been reported that might affect the criteria for ... read more
Research Article
Seyed Amir Aledavood, Soodabe Shahid Sales, Kazem Anvari, Mohammad Naser Forghani, Bahram Memar, Ali Emadi Torghabeh
Preoperative concurrent chemoradiotherapy may improve surgical results and patient survival rates in gastric adenocarcinomas. We aimed to assess tumor resectability and pathologic response rates in patients with locally advanced proximal gastric and esophagogastric junction adenocarcinomas by preoperative CRT and toxicity evaluation of treatment. The patients with proximal ... read more
Research Article
Hamid Reza Khorshidi, Mohammad Taheri, Rezvan Noroozi, Mohammad Soudyab, Arezou Sayad, Soudeh Ghafouri-Fard
Long non coding RNAs (lncRNAs) are of functional non coding RNAs which have been shown to be involved in several important pathways in cancer development and progression. Among them is Hox transcript antisense intergenic RNA (HOTAIR) whose overexpression has been detected in several cancer types. In addition, ... read more
Research Article
Mojtaba Rashidi, Atefeh Seghatoleslam, Mehdi Namavari, Ahmad Amiri, Mohammad Ali Fahmidehkar, Amin Ramezani, Ebrahim Eftekhar, Ahmad Hosseini, Nasrollah Erfani, Shima Fakher
Cancer is one of the major threatening factors of human health worldwide. Unfortunately, chemotherapy, the powerful arm of cancer therapy, is accompanied with many side effects, so alternative treatments with greater specificities and fewer side effects are highly required.Human cancer cell lines including SW-742, HCT116, HepG2, Hep2, ... read more
Case Report
Zohreh Yousefi, Shohreh Saied, Behrouz Davachi, Alireza Rezaei, Fatemeh Mirzamarjani
Choriocarcinoma is a gestational trophoblastic tumor that mainly affects women of childbearing age and rarely occurs in postmenopausal women especially following a long latent period from previous pregnancies. In this case report, we introduce three cases of postmenopausal choriocarcinoma with different clinical signs and symptoms.The first patient ... read more
Case Report
Mohsen Kolahdouzan, Seyed Hamid Reza Abtahi, Lotfallah Abedini, Hamid Reza Jafari, Elyas Mostafapour
Laryngeal adenoid cystic carcinoma (LACC) is a very rare cancer among laryngopharyngeal malignancies with varieties in presentation.Here, we discuss a case of 54-year-old female who was admitted in the emergency department with long-term dyspnea, hoarseness, and stridor. Cervicothoracic multi detector computed tomography (MDCT) scan showed a mass ... read more

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